We Don't Discover Cures, We Help YOU Engineer Them

AI-powered precision medicine platform that transforms genomic data into actionable therapeutic intelligence.

🏥

For Clinicians

Unified care plans in minutes

🔬

For Researchers

Validate targets in-silico

⚔️

For Biotech

Design therapeutics, not experiments

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Trusted By Leading Organizations

CrisPRO.ai builds trust through transparency and auditability. World-class research institutions and technology leaders trust us to accelerate breakthrough discoveries with honest limitations and evidence-backed recommendations.

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American Association for Cancer Research

Leading cancer research organization advancing the prevention and cure of cancer

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You Bring the Science, We Bring the AI Engineering

Validated in-silico predictions for variant impact, drug fit, and CRISPR design.

📊 53,210+ variants validated
🏆 State-of-the-art on ClinVar
🧬 No training required
Key Differentiator

SAE Explainability

32,768 learned biological features explain every prediction

100%
Transparent AI
32,768 SAE features
SOTA

ClinVar Validation

We Eliminate Failure at the Source.

95.7%
AUROC
53,210 variants validated
Clinical Grade

BRCA1/2 Precision

We eliminate the failure of clinical translation

95.0%
BRCA1 AUROC
3,893 variants analyzed
4x Better

Therapeutic Design

we design viable candidates from day one, not by chance

70%
Pfam-hit Rate
vs 18% previous models
Contract Ready

ROI for Biotechs

We Eliminate the Failure of Bankruptcy

80%
Cost Reduction
$2.5M → $500K per target

See All Performance Metrics

Explore our complete validation results, benchmark comparisons, and business impact analysis.Everything you need for due diligence and contract negotiations.

🔬 Peer-reviewed validation • 📊 Real-world benchmarks • 💼 Contract-ready analysis

Our Capabilities

Comprehensive in-silico tools for research oncology, from variant analysis to therapeutic guidance

Will It Work For Me?

Clinical Decision Support

Efficacy Confidence:70-85%%
Toxicity Prevention:100%%
Trial Match %:96.600%
Try WIWFM

Universal Hypothesis Testing

Research Acceleration

Diseases Supported:50.000+
Compounds Queryable:110M+
Hypothesis Validation:Hours
Explore Research Tools

Design Precision Interventions

Therapeutic Design

Guides Validated:100%%
Structural Confidence (pLDDT):70.000≥
FDA Docs Generated:Complete
Start Designing

Multi-Modal AI Validation

Platform Intelligence

S/P/E Weighting:30/40/30
Insights Chips:4.000
Audit Trails:Complete
See How It Works

Ask Questions Naturally

Conversational AI

Natural Language Parsing:High
Context Awareness:Sporadic-Aware
Multi-Intent Handling:Seamless
Try Co-Pilot

Production-Ready SaaS

Enterprise Platform

Database Schema:9.000tables
Pricing Tiers:3.000
Admin Controls:Complete
View Pricing

From 90% Failure to Predictable Success

Transform your drug development pipeline from gambling to engineering with our 3-stage in-silico platform. Every stage includes SAE explainability—see exactly what the AI is thinking.👇 Scroll down to try each stage live with interactive demos.

STAGE 1🧠 See What AI Sees

Stage 1: Target Identification & Validation

From months of exploration to 60-second conquest

❌ The Problem
The Exploratory Phase Bottleneck
Cost: $2.5M per target
Time: 18 months average
Failure Rate: 85% false positives
✅ Our Solution
60-Second In-Silico Conquest

Mathematical proof of functional disruption + Achilles' heel confirmation

Business Impact
Cost Reduction
99.8%
Time Reduction
72x faster
Success Rate
6x improvement
Validated Performance
BRCA1 AUROC95.0%
ClinVar SOTA95.7%
STAGE 2🧠 See What AI Sees

Stage 2: Lead Discovery & Optimization

We don't discover leads; we engineer them

❌ The Problem
The Screening Bottleneck
Cost: Millions of molecules screened
Time: 2-3 years optimization
Failure Rate: 99.9% candidates fail
✅ Our Solution
Zeta Forge: Therapeutic Engineering

First-principles design with embedded optimization

Business Impact
Cost Reduction
95%
Time Reduction
Years → Hours
Success Rate
Multiple candidates per command
Validated Performance
Pfam-hit Rate70%
Structural ValidationAlphaFold 3 confirmed
STAGE 3🧠 See What AI Sees

Stage 3: Pre-Clinical Confirmation

From expensive wet-lab to near-zero-cost in-silico trial

❌ The Problem
The Validation Gate
Cost: Expensive wet-lab confirmation
Time: 6-12 months
Failure Rate: 70% fail at this stage
✅ Our Solution
In-Silico Trial Validation

Cellular-level simulation + structural proof of mechanism

Business Impact
Cost Reduction
90%
Time Reduction
Months → Days
Success Rate
High-certainty candidates only
Validated Performance
DMS CorrelationStrong correlation
Structural OracleAlphaFold 3 integration
See Live 3-Stage Pipeline Demo

Discovery vs. Engineering

The fundamental shift from a game of chance to a discipline of creation.

The Old Way: A Funnel

Low-probability screening

Millions of Molecules

Searching...

0.0 months
Timeline
$0.0M
Cost

The New Doctrine: A Factory

High-certainty generation

🧠 SAE Explainability

Explore

AI Engineering

Engineering...

Validated & Patent-Ready

0.0 weeks
Timeline
$0.00M
Cost

The Transformation

We've replaced the needle-in-haystack approach with precision engineering. Every therapeutic candidate is designed for success, not discovered by chance.

🧬
Research

Try it live: Experience the complete drug development pipeline powered by AI. Select a stage above to run an interactive demo with real variants and see SAE explainability in action.

Research Use Only - Simulated Results
From Target Validation to Therapeutic Dossier (RUO)

Target Validation

Hereditary Breast Cancer Triage

Performance
95.7% ClinVar AUROC
Eliminates $2.1M target validation costs
API Pipeline
/predict_variant_impact/predict_protein_functionality_change/predict_chromatin_accessibility

Ready to Build Your Next Cancer Drug?

This demonstration will show you how to go from a genetic variant to a validated therapeutic target using our complete AI-powered drug development pipeline.

Research Use Only - Simulated Results

R&D ROI Calculator

Calculate Your R&D ROI Improvement

See exactly how CrisPRO's AI reduces failure costs and accelerates your pipeline.Real ROI calculations for biotech executives.

90%
Success Rate
72x
Faster Validation
$12M+
Annual Savings
6x
ROI Multiple
Biotech ROI Calculator

Calculate Your R&D ROI Improvement

See exactly how CrisPRO's AI reduces failure costs and accelerates your pipeline

🚀 Watch live simulation with industry data

Live ROI Simulation

Current Industry Reality
$20.0M/mo
R&D Investment
15%
Success Rate
10/year
Targets Validated
18mo
Validation Time
CrisPRO Transformation
95.7% AUROC
Oracle Accuracy
1 week
Validation Time
90% success
Target Success Rate
72x faster
Speed Improvement
CrisPRO Target Analysis

Target Validation Score

FAILVALID

+18,420

VALIDATED TARGET

Oracle AI validating therapeutic target in real-time

CrisPRO ROI Impact

Current Monthly Failures
$0K

Wasted on failed targets (85% failure rate)

Monthly Savings
Calculating...

Saved by reducing target validation failures

Success Rate
90%

vs 15% current (+0% improvement)

Validation Speed
0x faster

18 months → 1 week with Oracle AI

Annual ROI
0.0x

Return on CrisPRO investment ($2M/year)

What This Means for Your Pipeline:
Validate 0 more targets per year
De-risk 0 additional programs
95.7% accuracy vs 15% current
Focus wet-lab resources on validated targets only

Ready to Transform Your Numbers?

Schedule a demo to see how these savings apply to your specific programs

Schedule Executive DemoSee All Metrics

Eliminate the $2.6B gamble with mathematical certainty.

Join the biotech leaders who've eliminated the $2.6B gamble with mathematical certainty. Transform your R&D pipeline from gambling to engineering.