We Don't Discover Cures, We Help YOU Engineer Them

Our In-Silico Therapeutics Platform doesn't replace experiments. It help you choose WHICH experiments to run.

✅ 95.7% Target Validation
🧬 1 million token context
⚡Research-Use-Only

⚡ No signup required • See results in 30 seconds • Try real genetic variants

Initializing Editor...
Cas9 Protein • PAM: NGG • 1,368 aa
On-target score: 0.92
Off-target sites: 2

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CrisPRO.ai is trusted by world-class research institutions and technology leaders to accelerate and secure breakthrough discoveries in cancer research and therapeutic development.

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American Association for Cancer Research

Leading cancer research organization advancing the prevention and cure of cancer

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UC Berkeley

Premier public research university driving innovation in biotechnology and genomics

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You Bring the Science, We Bring the AI Engineering

Validated in-silico predictions for variant impact, drug fit, and CRISPR design.

📊 53,210+ variants validated
🏆 State-of-the-art on ClinVar
🧬 No training required

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SOTA

ClinVar Validation

We Eliminate Failure at the Source.

95.7%
AUROC
53,210 variants validated
Clinical Grade

BRCA1/2 Precision

We eliminate the failure of clinical translation

95.0%
BRCA1 AUROC
3,893 variants analyzed
4x Better

Therapeutic Design

we design viable candidates from day one, not by chance

70%
Pfam-hit Rate
vs 18% previous models
Contract Ready

ROI for Biotechs

We Eliminate the Failure of Bankruptcy

80%
Cost Reduction
$2.5M → $500K per target

See All Performance Metrics

Explore our complete validation results, benchmark comparisons, and business impact analysis.Everything you need for due diligence and contract negotiations.

🔬 Peer-reviewed validation • 📊 Real-world benchmarks • 💼 Contract-ready analysis

🧬
Research

Experience the complete drug development pipeline powered by AI. From target validation to lead engineering to pre-clinical confirmation -all in-silico, all in minutes.

Research Use Only - Simulated Results
From Target Validation to Therapeutic Dossier (RUO)

Target Validation

Hereditary Breast Cancer Triage

End-to-end triage of BRCA1 variant with downstream context and actionability

Performance
95.7% ClinVar AUROC
Eliminates $2.1M target validation costs
API Pipeline:
/predict_variant_impact/predict_protein_functionality_change/predict_chromatin_accessibility

Ready to Build Your Next Cancer Drug?

This demonstration will show you how to go from a genetic variant to a validated therapeutic target using our complete AI-powered drug development pipeline.

Research Use Only - Simulated Results

Eliminate the $2.6B gamble with mathematical certainty.

Join the biotech leaders who've eliminated the $2.6B gamble with mathematical certainty. Transform your R&D pipeline from gambling to engineering.