The Operating System forZero-Shot Oncology
Transform drug development from high-risk discovery into deterministic engineering through continuous agentic intelligence.
We enable biotech companies, pharmaceutical researchers, and clinical oncologists to make evidence-backed treatment decisions using validated AI models for variant interpretation, therapeutic design, and real-time patient monitoring.
How We Transform Drug Development
Through continuous agentic intelligence, we enable complete end-to-end platforms that transform genomic data into actionable therapeutic intelligence.
Three integrated products: Precision Oncology for clinical decision support, R&D for therapeutic design, and Research for discovery acceleration.
Trusted By Leading Organizations
CrisPRO.ai builds trust through transparency and auditability. World-class research institutions and technology leaders trust us to accelerate breakthrough discoveries with honest limitations and evidence-backed recommendations.
American Association for Cancer Research
Leading cancer research organization advancing the prevention and cure of cancer
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UC Berkeley
Premier public research university driving innovation in biotechnology and genomics
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American Association for Cancer Research
Leading cancer research organization advancing the prevention and cure of cancer
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Partner With UsYou Bring the Science, We Bring the AI Engineering
Validated in-silico predictions for variant impact, drug fit, and CRISPR design.
Transform Drug Development with Continuous Agentic Intelligence
From upload to Month 18+, our agents never stop working—tracking, analyzing, and alerting you to critical changes automatically.
Upload Once
Genomic reports, clinical notes, lab results, imaging data
- •NGS reports (VCF, MAF, PDF)
- •Clinical notes and pathology reports
- •Lab results and imaging data
- •Complete patient context
Agents Orchestrate
8-agent pipeline extracts, analyzes, and generates insights automatically
- •Data Extraction Agent: Parses and validates data
- •Biomarker Agent: Calculates TMB, MSI, HRD
- •Synthetic Lethality Agent: Evo2-powered essentiality scoring
- •Drug Ranking Agent: S/P/E framework (96.6% accuracy)
- •Trial Matching Agent: Mechanism-based matching
- •Nutrition Agent: Toxicity-aware recommendations
- •Resistance Agent: Early detection predictions
- •Monitoring Agent: Continuous intelligence
Track Forever
Continuous monitoring never stops—alerts, updates, new insights
- •CA-125 kinetics tracking (plateau detection)
- •ctDNA mutation monitoring (KRAS G12D at 0.8% VAF)
- •New trial auto-matching (instant notifications)
- •Resistance alerts 3-6 weeks before imaging
- •Drug rankings updated as research emerges
- •Real-time dashboard with actionable insights
🧬 Research
Try it live: Experience the complete drug development pipeline powered by AI. Select a stage above to run an interactive demo with real variants and see SAE explainability in action.
Target Validation
Hereditary Breast Cancer Triage
Ready to Build Your Next Cancer Drug?
This demonstration will show you how to go from a genetic variant to a validated therapeutic target using our complete AI-powered drug development pipeline.
Research Use Only - Simulated Results
Calculate Your R&D ROI Improvement
See exactly how CrisPRO's AI reduces failure costs and accelerates your pipeline.Real ROI calculations for biotech executives.
Ready to Transform Your Numbers?
Schedule a demo to see how these savings apply to your specific programs