GPT vs CrisPRO: See the Difference
Real Benchmarks: Average MOAT Advantage 0.86
Compare real GPT responses with CrisPRO's genotype-informed, actionable recommendations. Based on 6-question benchmark showing CrisPRO's superiority in personalized genomics, pathway analysis, and evidence-backed dosages.
The Problem: Generic AI Can't Do Precision Medicine
GPT and other LLMs provide generic medical advice based on training data, but they lack the biological foundation models needed for genotype-specific, actionable recommendations.
Generic Responses
Same advice for everyone, regardless of genotype or pathway status.
No Pathway Analysis
Cannot analyze functional pathway disruptions or predict genotype-specific effects.
No Predictive Modeling
Cannot predict TMB, resistance, or synthetic lethality from genotype alone.
The Solution: Biological Foundation Models
CrisPRO uses Evo2 foundation models with 32,768 learned biological features to provide genotype-specific, pathway-informed recommendations that generic AI cannot match.
Genotype-Specific
YOUR MBD4 deficiency means BER pathway is impaired. Specific recommendations based on YOUR genotype.
Pathway-Informed
Functional pathway analysis enables synthetic lethality detection, TMB prediction, and timing protocols.
Actionable
Precise recommendations: "Stop NAC 24h before, resume 24h after" - not generic "avoid antioxidants".
Real Benchmarks: GPT vs CrisPRO
Compare real GPT responses with CrisPRO's genotype-informed recommendations. See the difference in action.
Personalized supplements with dosages, mechanisms, and timing
Patient AK
What foods or supplements can help mitigate toxicity for a patient with BRCA1 variant receiving carboplatin?
Patient has BRCA1 variant and is scheduled for platinum-based chemotherapy (carboplatin).
GPT/ChatGPT
- Generic advice (same for everyone)
- No variant-specific analysis
- No mechanism explanation
- No dosages or timing
- No evidence citations
CrisPRO.ai
Based on your BRCA1 variant, platinum-based chemotherapy creates significant DNA repair stress. Here are specific recommendations:
Post-Infusion Supplements (not during infusion):
1. NAC (N-acetylcysteine): 600mg twice daily
- Mechanism: BRCA1 variant + platinum → DNA repair stress → BER pathway overload
- Timing: Post-infusion (not during) to avoid interfering with chemotherapy efficacy
2. Vitamin D: 5000 IU daily
- Supports DNA repair pathways and immune function
3. Folate: 400-800mcg daily
- Critical for DNA synthesis and repair
Evidence Tier: MODERATE
Rationale: BRCA1 variant increases sensitivity to platinum-induced DNA damage. These supplements support BER pathway function without interfering with chemotherapy mechanism.
Compare Against Competitors
Select additional competitors to compare (coming soon)
Competitor selection UI will be added here
Foundation Medicine, Tempus, Guardant Health, etc.