Oracle

Direct Guide RNA Cutting Efficiency Prediction

POST /predict_crispr_spacer_efficacy

Predicts the on-target functional efficacy (likelihood of successful cutting/activity) of a CRISPR guide RNA spacer sequence directly from its sequence.

Parameters

taskstringRequired

The API task identifier

Example: predict_crispr_spacer_efficacy

sequencestringRequired

Parameter: sequence

Example: GACGGAGGCTAAGCGTCGCAA

Code Examples

Python Example

PYTHON

import requests

response = requests.post(
    "https://api.crispro.ai/predict_crispr_spacer_efficacy",
    headers={"Authorization": "Bearer YOUR_API_KEY"},
    json={
    "task": "predict_crispr_spacer_efficacy",
    "sequence": "GACGGAGGCTAAGCGTCGCAA"
}
)

result = response.json()
print(result)

cURL Example

CURL

curl -X POST https://api.crispro.ai/predict_crispr_spacer_efficacy \
  -H "Authorization: Bearer YOUR_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"task":"predict_crispr_spacer_efficacy","sequence":"GACGGAGGCTAAGCGTCGCAA"}'

Response Schema

{
  "efficacy_score": "string",
  "efficacy_prediction": "string",
  "likelihood_of_interaction_change": "string"
}