Oracle

Protein-Level Functional Impact

POST /predict_protein_functionality_change

Predicts the change in a protein's overall function, stability, or binding affinity given its sequence and a proposed mutation or modification.

Parameters

taskstringRequired

The API task identifier

Example: predict_protein_functionality_change

wt_sequencestringRequired

Parameter: wt_sequence

Example: MDSKG...

mut_sequencestringRequired

Parameter: mut_sequence

Example: MDSKE...

Code Examples

Python Example

PYTHON

import requests

response = requests.post(
    "https://api.crispro.ai/predict_protein_functionality_change",
    headers={"Authorization": "Bearer YOUR_API_KEY"},
    json={
    "task": "predict_protein_functionality_change",
    "wt_sequence": "MDSKG...",
    "mut_sequence": "MDSKE..."
}
)

result = response.json()
print(result)

cURL Example

CURL

curl -X POST https://api.crispro.ai/predict_protein_functionality_change \
  -H "Authorization: Bearer YOUR_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"task":"predict_protein_functionality_change","wt_sequence":"MDSKG...","mut_sequence":"MDSKE..."}'

Response Schema

{
  "protein_functionality_score_change": "string",
  "predicted_stability_change": "string",
  "folding_impact_score": "string"
}