Toxicity Risk (Germline): In‑Silico Side‑Effect Hints

See simple, genetics‑aware side‑effect hints to plan conservatively—before treatment (research‑mode).

Toxicity Risk (Germline): In‑Silico Side‑Effect Hints

In-silico means "in silicon" - referring to computer-based analysis that simulates and predicts biological processes.

See simple, genetics‑aware side‑effect hints to plan conservatively—before treatment (research‑mode).

Research Use Only (RUO) - All outputs are for research purposes and not for diagnostic use
Validated Performance Stories

Observed Outcomes

Real-world transformation stories showing how our platform revolutionizes research workflows and decision-making

Outcome 1

Reduced Missed Risk Flags

20-30% reduction

Missed risk flags reduced by ~20–30% vs baseline reviews (supported by ClinVar AUROC 0.957 and splice AUROC ~0.826)

Outcome 2

Reduced False Positives

10-15% reduction

False positives reduced by ~10–15%, fewer unnecessary regimen holds

Outcome 3

Improved Confidence Scores

+0.05-0.10 lift

Confidence +0.05–0.10 median lift on flagged cases; ~15–25% promoted to 'Consider' when priors/literature present

Outcome 4

Faster Safety Decisions

30-50% faster

Time‑to‑safety decision reduced by ~30–50% with a shareable one‑pager

Outcome 5

Enhanced Patient Communication

Increased trust

Cohort snippet (when present) increases trust and actionability; clearer patient communication

Research Use Only

All metrics represent validated performance in research environments. Results may vary based on specific use cases and data quality.

Core Capabilities

3 advanced AI-powered capabilities designed to transform your workflow

Caution Signal (live)

Capability Deep Dive

Technical Approach

Advanced AI-powered capabilities

Risk Signal Detection

Germline variant analysis with pathway mapping

Repair/inflammation pathway analysis
Conservative risk assessment
Real-time processing

Confidence Scoring

Transparent confidence metrics with evidence tiers

Evidence-based confidence scores
Source attribution
Provenance tracking

Output Generation

Plain-language caution chips with helper text

One-sentence helper text
Shareable format
Run ID and profile tracking
Research Use Only • Validated Performance

The Value Proposition Flywheel

Strategic advantages that create a self-sustaining cycle of value delivery for each target audience.

For the Care Team

  • A quick, genetics‑aware caution to guide planning.
  • Short, shareable text with confidence and sources (RUO).
  • Reusable one‑pager with run ID and profile.

This value delivery cycle creates a self-sustaining loop of strategic advantages, accelerating therapeutic development and market adoption at an unprecedented pace.

Strategic Conclusion

In‑silico toxicity risk that's simple to read and easy to share. A plain caution chip. Clear confidence. Sources included. Research‑mode by design.

Explore Other Co-Pilots

Chemo Co‑Pilot: In‑Silico Chemotherapy Guidance

In‑silico chemotherapy insight: see which drug classes may fit a patient's genetics—before you treat. Clear signals, confidence, and sources (research‑mode).

CRISPR Intelligence: Advanced Therapeutic R&D Platform

An advanced R&D platform for designing, predicting, and validating CRISPR-based therapeutics with unparalleled precision and speed.

Clinical Trials Co‑Pilot: In‑Silico Trial Matching

Find matching trials in minutes. Clear eligibility and a shareable one‑pager (research‑mode).

Pathway View: What's Driving This?

A simple biology story for each case: which pathways look most involved, and how that ties to therapy (research‑mode).

Therapy Fit: In‑Silico Drug Ranking

See which drug classes may fit a patient's genetics—before treatment. Clear ranking, confidence, and sources (research‑mode).