How can we prevent dangerous side effects before they happen?
100% PGx coverage prevents life-threatening toxicity before treatment starts. Personalized dosing with 83.1% toxicity reduction (PREPARE trial).
We've built the first system that prevents drug toxicity by identifying germline risks and recommending protective foods.
The Problem: Life-Threatening Toxicity Discovered Too Late
For patients with advanced, heavily pretreated cancer, clinicians need to know: ...
Pharmacogene Variants Undetected
DPYD, TPMT, UGT1A1 variants cause severe toxicity but aren't routinely screened
Pathway Overlap Unknown
Drug MoA overlaps with patient's germline vulnerabilities, multiplying risk
Generic Nutrition Advice
Patients get generic 'eat healthy' instead of pathway-specific foods
The Solution: Toxicity-Aware Nutrition
We've built the first system that prevents drug toxicity by identifying germline...
Toxicity Pathway Detection
Identifies which biological pathways your drug stresses
Mitigating Foods Mapping
Knows which foods support those pathways
Personalized Timing
Knows when to take supplements (during vs
How Level 4 Works
Four steps to unlock this capability
Take CSI Score, Drug Selection, and Resistance Prediction from Levels 1-3
Add Genetic Safety Screening (PGx)
Predict Toxicity Risk and Pathway Overlap
Personalized Dosing and Protective Nutrition
CSI in Action: Continuous Monitoring
See how CSI updates automatically as tumor evolves. Track chemosensitivity across treatment lines with real-time alerts when CSI drops below threshold.
Level 4: Safety & Dosing
Prevent dangerous side effects before they happen
CSI Continuous Monitoring
Track CSI score updates as tumor evolves. Never miss a chemosensitivity change. • Patient AK
ChemoSensitivity Index
3/6/2026
Tumor Marker
2/28/2026
CT Scans
2/14/2026
Liquid Biopsy
3/6/2026
Clinical Trials
3/5/2026
Early Warnings
Recent
Active Alerts & Insights
4 ActiveCSI Score Decreased
Your CSI score dropped, meaning chemo is becoming less effective
CA-125 Plateau
Your CA-125 stopped declining and is staying flat
Resistance Mutation
New mutation detected in your blood that makes cancer resistant to current treatment
New Trial Match
A clinical trial that matches your specific tumor biology just opened
Next: Level 5 - Complete Care Plan
Complete treatment timeline showing progression across all treatment lines
Level 4 Performance Metrics
Validated performance for this capability
Validation Status
Validated performance for this capability